Inside the Science of Longevity: Meet the Suppliers Shaping the Future

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• The New Era of Ageless Beauty
• Why Longevity Matters
• The Suppliers Powering Long-Term Skin Health 
• Turning Longevity Vision Into Reality

The New Era of Ageless Beauty

Beauty trends come and go. But one movement is proving it’s here to stay: longevity. Behind every game-changing product is a supplier pushing boundaries, fine-tuning ingredients, and dreaming up what’s next for skin longevity. 

There are suppliers going beyond the brief, developing bioavailable actives, pioneering green chemistry, and delivering the kind of R&D that helps brands stay five steps ahead. In this round-up, we’ve gathered the standouts who are setting new standards. 

Explore the behind-the-scenes innovators who are quietly (and not so quietly) shaping the future of longevity in beauty.

Why Longevity Matters

Longevity in beauty isn’t just about turning back the clock (at least, not anymore). As the lines between skincare, wellness, and self-care continue to blur, longevity has emerged as a guiding principle that ties it all together. Consumers are no longer content with quick fixes, they’re seeking state of the art products that work with the skin’s natural processes. 

Longevity isn’t just skin deep, it’s also about responsible innovation through: 

• Sustainable formulations 
• Ingredients with traceable sourcing 
• Packaging that doesn’t outlive the product by a few hundred years 

For brands, tapping into the longevity space means building deeper trust, fostering brand loyalty, and staying relevant in a landscape that’s moving towards more intentional beauty. And the suppliers leading this charge? …Continue reading, and we’ll show you who you have to look out for. 

💡Covalo tip: Did you know you can bookmark ingredients from your favorite suppliers on Covalo? Just click the purple star next to the ingredient!

The Suppliers Powering Long-Term Skin Health 

1. ALGAKTIV

ALGAKTIV® is a pioneer in marine and microalgae biotechnology, dedicated to unlocking the extraordinary resilience of microalgae to power innovative skincare solutions. With a deep commitment to clean science and wellness-led beauty, ALGAKTIV bridges biotechnology and skin longevity – by offering ingredients designed to work in harmony with the skin’s natural processes.

Their newest active, ALGAKTIV Exometics G (who recently won Bronze for best active ingredient at in-cosmetics Korea 2025!), harnesses the natural defense strategies of extremophile microalgae to deliver a unique variety of postbiotics and exosome-like vesicles.  Their unique benefits include helping the skin resist stress, boost cellular communication, and promote longevity from within. 

2. Caffe Inc.

Based in Amsterdam, Caffe Inc. takes an eco-fashion-forward approach by rescuing spent coffee grounds and transforming them into beauty gold. Their ingredient Upcycled Booster In-Key is a multifunctional powerhouse brimming with all natural anti-aging heavyweights: 

• Polyphenols 
• Tocopherols (Vitamin E) 
• Omega-3 
• Omega-6
• Fatty Acids 
• Caffeine

This active delivers powerful antioxidant protection, helps strengthen the skin barrier and retains moisture, mild UV filtering, boosts circulation, and even supports skin elasticity. Created without harsh chemicals, it’s a perfect fit for longevity-focused formulations that aim for efficacy and ethics. It’s vegan, circular, and COSMOS certified! With every ton of coffee waste processed, Caffe Inc. also saves approximately 400Kg of CO₂, proving that longevity in skincare can go hand-in-hand with a healthier planet. 

3. CLR Berlin 

Berlin-based CLR crafts high-performance actives that fuse scientific rigor with natural efficacy, and their freshly relaunched duo – CutiGuard CLR™ and G+C Complex CLR™, are redefining longevity in skin and hair care. 

• CutiGuard CLR™, derived from the resilient red alga Galdieria sulphuraria, takes cellular-level approach to longevity. It activates selective autophagy and helps clear senescent cells by targeting key markers like p62 and HMB1. In a 3% formulation, 76% of study participants preferred treated skin after just a 3-second glance. This is proof that longevity can also impact those vital first impressions. 
• G+C Complex CLR™, also known as Bifida Ferment Lysate, zeros in on the longevity trifecta: DNA damage repair, immunosuppression, and circadian rhythm balance. This COSMOS-approved postbiotic helps repair UV-induced CPD mutations, supports skin-immune balance, and combats inflammaging. 

Together, these actives illustrate CLR Berlin’s holistic approach: blending cutting-edge biotech with eco-conscious formulations to support skin resilience, health, and longevity.

4. Evolved By Nature 

Evolved By Nature has carved a niche with its Activated Silk™ peptides: naturally-derived, upcycled, and clinically validated for longevity in beauty. Their flagship peptides include: 

• Activated Silk™ 27P-α: The only natural pro-collagen peptide on the market, this powerhouse promotes Type I collagen synthesis and visibly reduces fine lines and wrinkles. Delivered via a slow-release hydrogel in professional-grade mesotherapy, it ensures long-lasting firmness and texture improvements.
• Activated Silk™ 8A-α: A tone-brightening peptide that targets hyperpigmentation to create a more even complexion. Clinically proven to reduce dark spots and boost radiance, it brings a holistic longevity solution. 

Their peptide library currently spans multiple high-performance actives, all engineered via a circular-economy biotech model that meets eight UN Sustainable Development Goals, proof that longevity can serve both skin and planet. 

5. Ínclita Seaweed Solutions 

Coming straight from Portugal, Ínclíta Seaweed Solutions (ISS) is a marine-biotech trailblazer with a mission to convert sustainably sourced seaweed into high-performance, clean beauty ingredients with long-term benefits. 

• InAlgae® AOX leads the charge as a deep-acting antioxidant and brightening active. Extracted fromFucus vesiculosus blended with linseed oil, AOX is rich in phlorotannins, fucoxanthin, zeaxanthin, B-carotene, and omega fatty acids. In clinical tests, it delivered 31% greater antioxidant power than green tea, and around 62% stronger tyrosinase inhibition versus kojic acid. This translates to improved defense against free radicals, reduced dark spots, and enhanced hydration and natural UN protection. 
• InAlgae® AZO, sourced from Azorean island seaweeds, packs polysaccharides and peptides that hydrate deeply, calm irritation, and offer gentle photoprotection. Lab results highlight its ability to reinforce the skin’s moisture barrier, neutralize oxidative stress, and soothe redness. 

Fully traceable. COSMOS/NATRUE-certified, and born from green-extraction biorefineries, these seaweed actives embody longevity on multiple levels: skin health, eco-conscious sourcing, and sustainable marine innovation. 

6. LipoTrue 

Barcelona-based LipoTrue brings together AI, marine biotech, plant biofactories, and big data to craft next-gen skincare ingredients centered on cellular longevity. Their R&D engine blends in silico peptide design, biomimicry, fermentation, and green chemistry to develop clinically backed actives that go beyond surface benefits. By targeting core longevity mechanisms they translate wellness science into tangible beauty outcomes. 

Cellaigie™ is LipoTrue’s AI-engineered peptide designed to induce “metaTORphosis” - a cellular fast akin to fasting or high-intensity interval training. In trials, it enhanced antioxidant capacity by 14% within 28 days and boosted skin luminosity by up to 26%, while reducing wrinkle depth by 12-30%.

7. Vytrus Biotech

Vytrus Biotech specializes in plant stem-cell technology, using the survival intelligence of resilient plants to boost skin’s own longevity mechanisms. Their actives mimic stress responses like fasting and detox to activate autophagy, protect telomeres, and energize cells – without compromising skin health or the planet. 

Their longevity standout ingredient? CLARIVINE™. Derived from Vitis vinifera stem cells under nutrient deprivation, this ingredient kickstarts cellular renewal through fastin-mimicry. It visibly enhances texture, glow, and smoothness while defending against oxidative stress and aging. A natural path to clearer, long-living skin. 

Turning Longevity Vision Into Reality

Behind every great longevity formulation is a supplier pushing its boundaries. Whether it’s harnessing nature’s survival secrets, decoding cellular renewal, or merging AI with advanced biotech, these innovators are bringing next-generation products for brands. 

What’s even more exciting? This is just the beginning! Learn more about longevity, and stay up to date with all news here. 

As demand grows for smarter, more sustainable longevity solutions, the partnerships we build today will shape the longevity landscape for years to come. 

Discover and connect with these trailblazing longevity suppliers on Covalo – and start creating your longevity products today!